SCHEMBL31537673

SCHEMBL31537673

COc1ncnc(C2CC2)c1-c1nc(OCc2ccc(-c3nc(C(F)(F)F)cn3C(C)C)cc2)c2c(OC)cccc2n1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.62
▸ WDR48 Q8TAF3 6/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31537658 0.94 USP1 (0.65) USP1WDR48
SCHEMBL31537696 0.89 USP1 (0.64) USP1WDR48
SCHEMBL31625492 0.88 USP1 (0.63) USP1WDR48
SCHEMBL31254951 0.87 USP1 (0.71) USP1WDR48
SCHEMBL31537632 0.86 USP1 (0.62) USP1WDR48
SCHEMBL31537628 0.86 USP1 (0.62) USP1WDR48
SCHEMBL31254969 0.85 USP1 (0.72) USP1WDR48
SCHEMBL31537617 0.85 USP1 (0.62) USP1WDR48
SCHEMBL31254888 0.83 USP1 (0.72) USP1WDR48
SCHEMBL31255132 0.83 USP1 (0.68) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096494-A1 UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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