Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31537758 | 0.85 | GAA (0.46) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL22443525 | 0.82 | SIGMAR1 (0.45) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL22444151 | 0.78 | SIGMAR1 (0.42) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL22444194 | 0.78 | SIGMAR1 (0.42) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL22443386 | 0.76 | SPHK2 (0.41) | SIGMAR1GBA1ACHE | |
| SCHEMBL22443385 | 0.76 | SPHK2 (0.41) | SIGMAR1GBA1ACHE | |
| SCHEMBL24047693 | 0.75 | MEN1 (0.46) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL10215483 | 0.75 | SIGMAR1 (0.40) | SIGMAR1MEN1TSHRKMT2AGAA | |
| SCHEMBL1393167 | 0.74 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL26071427 | 0.74 | SIGMAR1 (0.60) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056017-A1 | FUSED BICYCLIC HETEROARYLS AS PARG INHIBITORS AND USES THEREOF | ZAI LAB (SHANGHAI) CO., LTD. (CN) | 2025-03-20 | — | — | WO | disclosed |