Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31540760 | 0.90 | CACNA1I (0.58) | CACNA1IKCNH2ACHECCR3FURIN | |
| SCHEMBL21550897 | 0.86 | CACNA1I (0.54) | CACNA1IKCNH2ACHECCR3FURIN | |
| SCHEMBL30931839 | 0.86 | CACNA1I (0.54) | CACNA1IKCNH2ACHECCR3FURIN | |
| Hydrochloric Acid SCHEMBL29891250 | 0.85 | CACNA1I (0.53) | CACNA1IKCNH2ACHECCR3FURIN | |
| SCHEMBL31540798 | 0.85 | CACNA1I (0.53) | CACNA1IKCNH2TP53MAPTHTT | |
| SCHEMBL31540755 | 0.85 | CACNA1I (0.53) | CACNA1IKCNH2ACHECCR3FURIN | |
| SCHEMBL31540765 | 0.85 | CACNA1I (0.52) | CACNA1IKCNH2ACHEHDAC3HDAC4 | |
| SCHEMBL17469031 | 0.82 | ACHE (0.70) | ACHECXCR4HDAC3HDAC4HDAC1 | |
| SCHEMBL31540775 | 0.81 | CACNA1I (0.50) | CACNA1IKCNH2TP53MAPTHTT | |
| SCHEMBL27558611 | 0.81 | CCR2 (0.62) | CACNA1IKCNH2TP53ACHECXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068371-A1 | INHIBITORS OF THE PROPROTEIN CONVERTASE FURIN, METHODS OF PRODUCTION THEREOF AND USE | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2025-04-03 | — | — | WO | disclosed |