Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.47 |
| ▸ | UBE2M | P61081 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31540937 | 0.87 | DCUN1D1 (0.53) | DCUN1D1UBE2MALDH1A1LMNA | |
| SCHEMBL31540948 | 0.82 | DCUN1D1 (0.58) | DCUN1D1UBE2M | |
| SCHEMBL31540949 | 0.82 | TP53 (0.47) | DCUN1D1UBE2MTP53MEN1KMT2A | |
| SCHEMBL31540941 | 0.81 | NTRK1 (0.58) | DCUN1D1UBE2MTP53TDP1 | |
| SCHEMBL31540959 | 0.80 | NTRK1 (0.57) | DCUN1D1UBE2MTP53TDP1 | |
| SCHEMBL31540945 | 0.80 | UBE2M (0.48) | DCUN1D1UBE2MTP53ALDH1A1LMNA | |
| SCHEMBL31540943 | 0.79 | NTRK1 (0.57) | DCUN1D1UBE2MTP53TDP1ALDH1A1 | |
| SCHEMBL31540950 | 0.79 | NTRK1 (0.57) | DCUN1D1UBE2MTP53TDP1ALDH1A1 | |
| SCHEMBL31540951 | 0.77 | UBE2M (0.51) | DCUN1D1UBE2MTP53ALDH1A1POLB | |
| SCHEMBL31540958 | 0.77 | UBE2M (0.46) | DCUN1D1UBE2MTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998281-A | Neurotrophic receptor tyrosine kinase (NTRK) inhibitors and methods of use thereof | 贝勒医学院 | 2025-05-13 | — | — | CN | claimed |
| CN-119998281-A | Neurotrophic receptor tyrosine kinase (NTRK) inhibitors and methods of use thereof | 贝勒医学院 | 2025-05-13 | — | — | CN | disclosed |