Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31133152 | 0.87 | FFAR1 (0.37) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL31488070 | 0.87 | FFAR1 (0.42) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL760525 | 0.87 | FFAR1 (0.42) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL24456419 | 0.81 | KDM5B (0.36) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL15813615 | 0.80 | KDM5B (0.36) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL17069527 | 0.80 | KDM5B (0.35) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL1912961 | 0.79 | KDM5B (0.34) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL23699731 | 0.79 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL20953116 | 0.76 | KDM5B (0.37) | KDM5BFGFR1FLT3FGFR2FGFR4 | |
| SCHEMBL31510377 | 0.74 | KDM5B (0.40) | KDM5BFGFR1FLT3FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136587-A1 | N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC | 2025-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136587-A1 | N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS | TRPA1, TRPV1, SLC28A1 | KDM5B 3960/4885FGFR1 1436/4885FLT3 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.