Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.72 |
| ▸ | FLT3 | P36888 | 2/20 | 0.72 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.72 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.72 |
| ▸ | GAK | O14976 | 1/20 | 0.72 |
| ▸ | STK10 | O94804 | 1/20 | 0.72 |
| ▸ | YES1 | P07947 | 1/20 | 0.72 |
| ▸ | RET | P07949 | 1/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.72 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.72 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.72 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.72 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.72 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.72 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.72 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.72 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.72 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102539 | 1.00 | PIM1 (1.00) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL14653620 | 0.90 | PIM1 (0.81) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL24736882 | 0.88 | PIM1 (0.79) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL29555958 | 0.88 | PIM1 (0.79) | PIM1KCNH2FLT3PIM3PIM2 | |
| Sgi-1776 SCHEMBL29353896 | 0.83 | PIM1 (1.00) | PIM1KCNH2FLT3PIM3PIM2 | |
| Sgi-1776 SCHEMBL102498 | 0.83 | PIM1 (1.00) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL103384 | 0.81 | PIM1 (0.69) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL12761389 | 0.81 | PIM1 (0.74) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL2948807 | 0.81 | PIM1 (1.00) | PIM1KCNH2FLT3PIM3PIM2 | |
| SCHEMBL103225 | 0.80 | PIM1 (0.85) | PIM1KCNH2FLT3PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129085-A1 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS | SUMITOMO PHARMA AMERICA INC (US) | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129085-A1 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS | PIM1, PIM2, PIM3 | PIM1 1/4885KCNH2 1832/4885FLT3 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.