Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880474 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2PDE3BPDE3AAXLPDE4B | |
| SCHEMBL20702772 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL20703448 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2PDE3BPDE3APDE4BPDE2A | |
| SCHEMBL11627707 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2PDE3BPDE3AAXLPDE4B | |
| SCHEMBL11626246 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2PDE3BPDE3AAXLPDE4B | |
| SCHEMBL11657483 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2PDE3BPDE3AAXLPDE4B | |
| SCHEMBL11006840 | 0.71 | SMN1; SMN2 (0.62) | SMN1; SMN2PDE3BPDE3APDE4BPDE2A | |
| SCHEMBL10911962 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2PDE3BPDE3AAXLPDE4B | |
| SCHEMBL11634250 | 0.71 | PDE3B (0.50) | SMN1; SMN2PDE3BPDE3APDE4BPDE4A | |
| SCHEMBL7276201 | 0.71 | PDE3B (0.50) | SMN1; SMN2PDE3BPDE3APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638633-A | Method for preparing pyridazinone compound and application thereof | 深圳市华先医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |