Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17809644 | 1.00 | AXL (0.41) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL29471186 | 0.89 | AXL (0.44) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL20571990 | 0.89 | AXL (0.44) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL19369146 | 0.84 | LOXL2 (0.41) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL17806370 | 0.84 | ACVR1 (0.41) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL17795291 | 0.80 | KDM4E (0.51) | AXLLOXL2ACVR1PIK3CDPIK3CA | |
| SCHEMBL17864434 | 0.79 | PIM1 (0.39) | CYP11B1CYP11B2BRD4LRRK2PIM1 | |
| SCHEMBL24317104 | 0.77 | DYRK1A (0.40) | GSK3BDYRK1ALRRK2PIM1 | |
| SCHEMBL17785716 | 0.77 | KDM1A (0.48) | AXLLOXL2ACVR1OTUD7BPIK3CD | |
| SCHEMBL26552720 | 0.76 | PIM1 (0.49) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |