Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435245 | 0.88 | NPC1 (0.53) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL8446716 | 0.86 | NPC1 (0.51) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL16193419 | 0.85 | RAB9A (0.61) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL25734267 | 0.84 | NPC1 (0.49) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL20625743 | 0.83 | NPC1 (0.48) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL8446674 | 0.82 | NPC1 (0.47) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL20571516 | 0.81 | NPC1 (0.51) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL15052260 | 0.81 | NPC1 (0.48) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL29906775 | 0.80 | SMN1; SMN2 (0.46) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL31331181 | 0.80 | NPC1 (0.72) | NPC1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |