Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542314 | 0.93 | P2RY14 (0.39) | GPR119KDM4EMAPTTHRBSCN9A | |
| SCHEMBL31542334 | 0.92 | KMT2A (0.38) | GPR119KDM4EMAPTTHRBSCN9A | |
| SCHEMBL31542350 | 0.87 | GPR119 (0.40) | GPR119KDM4EMAPTTHRBJAK2 | |
| SCHEMBL31542284 | 0.84 | JAK2 (0.36) | KDM4EKMT2AJAK2P2RY14 | |
| SCHEMBL31542292 | 0.81 | NOTCH1 (0.36) | GPR119JAK2 | |
| SCHEMBL31542311 | 0.81 | GPR119 (0.40) | GPR119KDM4EMAPTTHRBHRH3 | |
| SCHEMBL31542329 | 0.78 | ALK (0.35) | GPR119JAK2HRH3 | |
| SCHEMBL31542349 | 0.78 | HRH3 (0.35) | GPR119JAK2HRH3 | |
| SCHEMBL31542308 | 0.77 | KDM4E (0.47) | GPR119KDM4EMAPTTHRBSCN9A | |
| SCHEMBL31425931 | 0.75 | PDE4B (0.48) | GPR119KDM4EMAPTTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |