Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23756437 | 0.84 | HTT (0.54) | HTTALOX15RXFP1CSNK2A1PTPN11 | |
| SCHEMBL31544152 | 0.82 | HTT (0.52) | HTTALOX15RXFP1CSNK2A1GRM1 | |
| SCHEMBL31544181 | 0.80 | CYP1A2 (0.51) | HTTALOX15RXFP1CSNK2A1MEN1 | |
| SCHEMBL31544230 | 0.80 | CYP1A2 (0.51) | HTTALOX15RXFP1CSNK2A1MEN1 | |
| SCHEMBL17658964 | 0.79 | KDM4E (0.57) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31544141 | 0.79 | ALDH1A1 (0.51) | HTTALOX15RXFP1CSNK2A1GRM1 | |
| SCHEMBL30133943 | 0.79 | CSNK2A1 (0.56) | HTTALOX15CSNK2A1MEN1KMT2A | |
| SCHEMBL5349000 | 0.79 | CSNK2A1 (0.56) | HTTALOX15CSNK2A1MEN1KMT2A | |
| SCHEMBL26617865 | 0.78 | RXFP1 (0.70) | RXFP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16945099 | 0.77 | KMT2A (0.71) | HTTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098450-A1 | PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR | 北京泰德制药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |