SCHEMBL31546379

SCHEMBL31546379

COc1ccc(-c2noc(N3CCC(c4nc5ccccc5[nH]4)CC3)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HTR2B P41595 1/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ ALDH1A1 P00352 3/20 0.52
▸ HTT P42858 3/20 0.52
▸ MAPT P10636 7/20 0.51
▸ LMNA P02545 4/20 0.51
▸ TP53 P04637 5/20 0.51
▸ THRB P10828 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546361 0.84 MAPT (0.53) HTR2BSMN1; SMN2MEN1KMT2APOLB
SCHEMBL25402791 0.81 MEN1 (0.59) SMN1; SMN2MEN1KMT2APOLBALDH1A1
SCHEMBL30584891 0.81 MEN1 (0.60) SMN1; SMN2MEN1KMT2APOLBMAPT
Formic Acid SCHEMBL31546421 0.79 MAPT (0.53) HTR2BSMN1; SMN2MEN1KMT2APOLB
SCHEMBL25434031 0.78 MEN1 (0.59) SMN1; SMN2MEN1KMT2APOLBALDH1A1
SCHEMBL1298886 0.76 HTR2B (1.00) HTR2BSMN1; SMN2ALDH1A1LMNA
SCHEMBL20463456 0.74 HTR2B (0.60) HTR2BSMN1; SMN2KMT2APOLBALDH1A1
SCHEMBL25403067 0.74 MAPT (0.61) SMN1; SMN2MEN1KMT2APOLBALDH1A1
SCHEMBL25400988 0.73 MEN1 (0.67) SMN1; SMN2MEN1KMT2APOLBALDH1A1
SCHEMBL30584791 0.73 MAPT (0.63) MEN1KMT2APOLBALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 HTR2B 4574/4885SMN1; SMN2 3115/4885MEN1 1569/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 HTR2B 4574/4885SMN1; SMN2 3115/4885MEN1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback