SCHEMBL31546432

SCHEMBL31546432

COc1ccc(-c2noc(N3CCC(C(=O)NCCc4ccccc4)CC3)n2)cc1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.67
▸ KMT2A Q03164 5/20 0.67
▸ LMNA P02545 2/20 0.65
▸ MAPT P10636 2/20 0.62
▸ SMN1; SMN2 Q16637 1/20 0.60
▸ POLB P06746 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20116216 0.89 MAPT (0.62) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30506224 0.89 MAPT (0.62) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30584971 0.88 MEN1 (0.66) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546422 0.88 MEN1 (0.72) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25435098 0.86 MEN1 (0.61) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546443 0.84 MEN1 (0.84) MEN1KMT2ALMNAMAPTSMN1; SMN2
Formic Acid SCHEMBL31546365 0.83 MEN1 (0.68) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25439443 0.83 MEN1 (0.60) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546397 0.83 MEN1 (0.60) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546358 0.83 MEN1 (0.73) MEN1KMT2ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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