SCHEMBL25435098

SCHEMBL25435098

COc1ccc(-c2noc(N3CCC(C(=O)NCC(O)Cc4ccccc4)CC3)n2)cc1

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.61
▸ KMT2A Q03164 4/20 0.61
▸ LMNA P02545 2/20 0.61
▸ MAPT P10636 2/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ POLB P06746 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546432 0.86 MEN1 (0.67) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30584810 0.84 LMNA (0.65) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30584971 0.82 MEN1 (0.66) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546330 0.81 MEN1 (0.72) MEN1KMT2ALMNAMAPTSMN1; SMN2
Formic Acid SCHEMBL31546417 0.81 KMT2A (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546443 0.81 MEN1 (0.84) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546422 0.81 MEN1 (0.72) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL31546397 0.80 MEN1 (0.60) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25432804 0.80 MEN1 (0.62) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25438262 0.80 LMNA (0.62) MEN1KMT2ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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