SCHEMBL31546711

SCHEMBL31546711

O=C1CCC(N2Cc3cc(-n4cc(-c5nccs5)nn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.53
▸ IKZF2 Q9UKS7 10/20 0.46
▸ CSNK1A1 P48729 1/20 0.43
▸ IKZF1 Q13422 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546770 0.83 CRBN (0.58) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546851 0.81 CRBN (0.56) CRBNIKZF2CSNK1A1
SCHEMBL31546766 0.81 IKZF2 (0.51) CRBNIKZF2CSNK1A1
SCHEMBL31546810 0.80 IKZF2 (0.49) CRBNIKZF2CSNK1A1
SCHEMBL31546795 0.80 IKZF2 (0.49) CRBNIKZF2CSNK1A1
SCHEMBL31546764 0.80 IKZF2 (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546808 0.80 CRBN (0.48) CRBNIKZF2
SCHEMBL31546761 0.80 CRBN (0.52) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546839 0.80 IKZF2 (0.53) CRBNIKZF2CSNK1A1
SCHEMBL31546910 0.80 CRBN (0.51) CRBNIKZF2CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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