SCHEMBL31546808

SCHEMBL31546808

COc1nccc(-c2cn(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nn2)n1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 7/20 0.48
▸ IKZF2 Q9UKS7 12/20 0.45
▸ WIZ O95785 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546766 0.90 IKZF2 (0.51) CRBNIKZF2WIZ
SCHEMBL31546886 0.87 IKZF2 (0.48) CRBNIKZF2
SCHEMBL31546827 0.86 CRBN (0.48) CRBNIKZF2
SCHEMBL31546764 0.86 IKZF2 (0.48) CRBNIKZF2
SCHEMBL31546742 0.86 CRBN (0.48) CRBNIKZF2
SCHEMBL31546687 0.86 CRBN (0.48) CRBNIKZF2WIZ
SCHEMBL31546739 0.85 CRBN (0.47) CRBNIKZF2
SCHEMBL31546753 0.85 IKZF2 (0.51) CRBNIKZF2WIZ
SCHEMBL31546855 0.85 IKZF2 (0.49) CRBNIKZF2
SCHEMBL31546894 0.85 IKZF2 (0.56) CRBNIKZF2WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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