SCHEMBL31546753

SCHEMBL31546753

COc1cc(-c2cn(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nn2)ncn1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 12/20 0.51
▸ CRBN Q96SW2 5/20 0.48
▸ IKZF1 Q13422 1/20 0.44
▸ WIZ O95785 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546827 0.89 CRBN (0.48) IKZF2CRBNIKZF1
SCHEMBL31546764 0.88 IKZF2 (0.48) IKZF2CRBN
SCHEMBL31546855 0.87 IKZF2 (0.49) IKZF2CRBNIKZF1
SCHEMBL31546766 0.87 IKZF2 (0.51) IKZF2CRBNWIZ
SCHEMBL31546886 0.86 IKZF2 (0.48) IKZF2CRBN
SCHEMBL31546894 0.85 IKZF2 (0.56) IKZF2CRBNWIZ
SCHEMBL31546808 0.85 CRBN (0.48) IKZF2CRBNWIZ
SCHEMBL31546839 0.85 IKZF2 (0.53) IKZF2CRBNWIZ
SCHEMBL31546910 0.84 CRBN (0.51) IKZF2CRBNWIZ
SCHEMBL31546865 0.84 CRBN (0.53) IKZF2CRBNWIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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