SCHEMBL31546864

SCHEMBL31546864

COc1cccc(-c2cn(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nn2)c1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.48
▸ IKZF2 Q9UKS7 8/20 0.47
▸ CSNK1A1 P48729 4/20 0.45
▸ WIZ O95785 1/20 0.45
▸ STIM1 Q13586 1/20 0.45
▸ ORAI1 Q96D31 1/20 0.45
▸ KEAP1 Q14145 1/20 0.44
▸ NFE2L2 Q16236 1/20 0.44
▸ CA12 O43570 1/20 0.44
▸ CA1 P00915 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546850 0.91 IKZF2 (0.48) CRBNIKZF2CSNK1A1WIZCA12
SCHEMBL31546910 0.91 CRBN (0.51) CRBNIKZF2CSNK1A1WIZCA12
SCHEMBL31546925 0.90 IKZF2 (0.48) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31546765 0.88 WIZ (0.52) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31546766 0.87 IKZF2 (0.51) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31546764 0.86 IKZF2 (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546839 0.86 IKZF2 (0.53) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31546827 0.85 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546894 0.85 IKZF2 (0.56) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31546865 0.85 CRBN (0.53) CRBNIKZF2CSNK1A1WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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