SCHEMBL31546884

SCHEMBL31546884

O=C1CCC(N2Cc3cc(-n4cc(-c5ccc6[nH]ncc6c5)nn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CDC7 O00311 1/20 0.48
▸ CRBN Q96SW2 8/20 0.48
▸ JAK2 O60674 3/20 0.44
▸ ROCK2 O75116 3/20 0.44
▸ GSK3B P49841 3/20 0.44
▸ IKZF2 Q9UKS7 7/20 0.43
▸ CSNK1A1 P48729 1/20 0.41
▸ IKZF1 Q13422 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546727 0.89 CRBN (0.49) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546820 0.86 CRBN (0.48) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546779 0.85 CRBN (0.48) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546850 0.84 IKZF2 (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546828 0.82 CRBN (0.49) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546910 0.82 CRBN (0.51) CRBNIKZF2CSNK1A1
SCHEMBL31546794 0.81 CRBN (0.49) CRBNIKZF2CSNK1A1IKZF1
SCHEMBL31546864 0.80 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546925 0.79 IKZF2 (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546770 0.79 CRBN (0.58) CRBNIKZF2CSNK1A1IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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