Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | DRD1 | P21728 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936092 | 0.83 | DRD2 (0.50) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23889000 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23888955 | 0.81 | DRD2 (0.55) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL26779153 | 0.80 | NQO1 (0.41) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23888958 | 0.80 | DRD2 (0.48) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23888967 | 0.79 | DRD2 (0.51) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23888996 | 0.79 | DRD2 (0.50) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL23888995 | 0.79 | DRD2 (0.48) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL26766343 | 0.78 | MAPT (0.42) | ALDH1A1NQO1MAPTNPC1RAB9A | |
| SCHEMBL25421596 | 0.77 | PLK4 (0.41) | ALDH1A1NQO1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072330-A1 | KIT INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-04-03 | — | — | WO | disclosed |