Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946 | 0.89 | HSD11B1 (0.34) | HSD11B1KCNK3KCNK9CHRM2CHRM1 | |
| SCHEMBL31505623 | 0.89 | HSD11B1 (0.34) | HSD11B1KCNK3KCNK9CHRM2CHRM1 | |
| SCHEMBL30797092 | 0.89 | HSD11B1 (0.34) | HSD11B1KCNK3KCNK9CHRM2CHRM1 | |
| SCHEMBL12537944 | 0.87 | HSD11B1 (0.38) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL16051305 | 0.84 | HSD11B1 (0.34) | HSD11B1KCNK3KCNK9CHRM2CHRM1 | |
| SCHEMBL30703 | 0.76 | — | — | |
| SCHEMBL41973 | 0.74 | CHRM2 (0.41) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL29336 | 0.74 | CHRM2 (0.41) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL16783751 | 0.74 | CHRM2 (0.41) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL2147759 | 0.72 | HSD11B1 (0.37) | HSD11B1CHRM2CHRM1CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |