Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16895024 | 0.81 | ELANE (0.44) | KMT2APKMTDP1MAPTKDM4E | |
| SCHEMBL226233 | 0.80 | TDP1 (0.47) | TDP1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL27388692 | 0.79 | LMNA (0.57) | KMT2AGAAALDH1A1PRSS1LMNA | |
| SCHEMBL13274370 | 0.79 | HPGD (0.46) | KMT2AMAPTCYP3A4TSHRLMNA | |
| SCHEMBL8975663 | 0.78 | TDP1 (0.48) | KMT2APKMTDP1MAPTKDM4E | |
| SCHEMBL11126719 | 0.78 | TDP1 (0.48) | KMT2APKMTDP1MAPTKDM4E | |
| SCHEMBL28622643 | 0.77 | TDP1 (0.44) | KMT2APKMTDP1MAPTKDM4E | |
| SCHEMBL27884399 | 0.75 | HSD17B10 (0.48) | KMT2AALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL4100461 | 0.75 | TDP1 (0.50) | KMT2APKMTDP1MAPTKDM4E | |
| SCHEMBL2132487 | 0.75 | TDP1 (0.50) | KMT2APKMTDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465963-B1 | PHOTOCHROMIC POLYMER COMPOSITIONS AND ARTICLES THEREOF | TRANSITIONS OPTICAL INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-20070001155-A1 | Photochromic polymer compositions and articles thereof | WALTERS ROBERT W | 2007-01-04 | — | — | US | disclosed |
| EP-1465963-A2 | PHOTOCHROMIC POLYMER COMPOSITIONS AND ARTICLES THEREOF | TRANSITIONS OPTICAL, INC. (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20030141490-A1 | Photochromic polymer compositions and articles thereof | TRANSITIONS OPTICAL, INC. | 2003-07-31 | — | — | US | disclosed |
| WO-2003056390-A2 | PHOTOCHROMIC POLYMER COMPOSITIONS AND ARTICLES THEREOF | TRANSITIONS OPTICAL, INC. (US) | 2003-07-10 | — | — | WO | disclosed |