Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486750 | 0.84 | BUB1 (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL18482861 | 0.84 | BUB1 (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL31549571 | 0.81 | BUB1 (0.44) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL19445998 | 0.79 | BUB1 (0.42) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL21625234 | 0.79 | CYP3A4 (0.37) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL31549576 | 0.78 | BUB1 (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL31549582 | 0.78 | ACLY (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL31549631 | 0.78 | BUB1 (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL31549680 | 0.78 | ACLY (0.39) | BUB1L3MBTL1BCHEHTR6HSP90AA1 | |
| SCHEMBL26128203 | 0.77 | BUB1 (0.40) | BUB1L3MBTL1BCHEHTR6HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068951-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2025-04-03 | — | — | WO | disclosed |