Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 8/20 | 0.93 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | AKT2 | P31751 | 4/20 | 0.72 |
| ▸ | GSK3B | P49841 | 3/20 | 0.72 |
| ▸ | KIT | P10721 | 2/20 | 0.72 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.69 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818852 | 0.97 | JAK3 (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL3959075 | 0.95 | JAK3 (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL2018963 | 0.95 | JAK3 (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL1048998 | 0.95 | JAK3 (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL2024857 | 0.88 | HTR2C (0.89) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL2251760 | 0.87 | HTR2C (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| Piperazine SCHEMBL7852092 | 0.85 | HTR2C (0.97) | JAK3HTR2CAKT2GSK3BKIT | |
| SCHEMBL31499276 | 0.85 | JAK3 (1.00) | JAK3HTR2CAKT2GSK3BKIT | |
| Hydrochloric Acid SCHEMBL2794687 | 0.85 | HTR2C (0.97) | JAK3HTR2CAKT2GSK3BKIT | |
| Hydrochloric Acid SCHEMBL29036000 | 0.85 | HTR2C (0.97) | JAK3HTR2CAKT2GSK3BKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968373-A | Aromatic heterocyclic compound and preparation method thereof | 上海翊石医药科技有限公司 | 2025-05-09 | — | — | CN | disclosed |