Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878893 | 0.78 | GAA (0.45) | EPHX2DPP8DPP9GAARIPK1 | |
| SCHEMBL4066845 | 0.78 | GAA (0.45) | EPHX2DPP8DPP9GAARIPK1 | |
| SCHEMBL31552619 | 0.76 | EPHX2 (0.59) | EPHX2NPY5R | |
| SCHEMBL9024887 | 0.75 | RIPK1 (0.40) | SCN9ADPP8DPP9TRPV1RIPK1 | |
| SCHEMBL13783986 | 0.74 | RIPK1 (0.46) | EPHX2GAARIPK1 | |
| SCHEMBL1270296 | 0.73 | RIPK1 (0.58) | EPHX2TRPV1GAARIPK1 | |
| SCHEMBL1270295 | 0.73 | RIPK1 (0.58) | EPHX2TRPV1GAARIPK1 | |
| SCHEMBL14391619 | 0.73 | RIPK1 (0.47) | EPHX2GAARIPK1 | |
| SCHEMBL1269028 | 0.73 | RIPK1 (0.52) | EPHX2GAARIPK1 | |
| SCHEMBL1269024 | 0.73 | RIPK1 (0.52) | EPHX2GAARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077767-A1 | NOVEL I-TYPE TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |