SCHEMBL3155282

SCHEMBL3155282

CNc1cc(CNc2ncccc2C(=O)Nc2ccc3c(c2)NC(=O)C3(C(F)(F)F)C(F)(F)F)ccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 15/20 0.55
KIT P10721 5/20 0.55
BRAF P15056 5/20 0.55
CIT O14578 1/20 0.55
MAP3K7 O43318 1/20 0.55
RIPK2 O43353 1/20 0.55
STK10 O94804 1/20 0.55
MAP4K4 O95819 1/20 0.55
ABL1 P00519 1/20 0.55
EGFR P00533 1/20 0.55
RAF1 P04049 1/20 0.55
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55
CSF1R P07333 1/20 0.55
YES1 P07947 1/20 0.55
LYN P07948 1/20 0.55
RET P07949 1/20 0.55
HCK P08631 1/20 0.55
PDGFRB P09619 1/20 0.55
FGR P09769 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143165 0.89 KDR (0.66) KDRKITBRAFCITMAP3K7
SCHEMBL3145610 0.89 KDR (0.53) KDRKITBRAFCITMAP3K7
SCHEMBL3144991 0.86 KIT (0.51) KDRKITBRAFCITMAP3K7
SCHEMBL3159208 0.85 KDR (0.51) KDRKITBRAFCITMAP3K7
SCHEMBL3150757 0.83 KDR (0.64) KDRKITBRAFCITMAP3K7
SCHEMBL3144781 0.82 KDR (0.81) KDRKITBRAFCITMAP3K7
SCHEMBL13417840 0.81 KDR (0.69) KDRKITBRAFCITMAP3K7
SCHEMBL13417728 0.81 KDR (0.66) KDRKITBRAFCITMAP3K7
SCHEMBL3154986 0.77 KDR (0.63) KDRKITBRAFCITMAP3K7
SCHEMBL3145941 0.77 KDR (0.58) KDRKITBRAFCITMAP3K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110368887-B Preparation method of amino substituted compound 北京六合宁远科技有限公司 2021-07-30 CN claimed
EP-2839873-B1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF WANG ZHIJUN (CN) 2017-01-04 EP claimed
EP-3022316-A1 MEANS AND METHODS FOR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) ANALYSIS IN A BIOLOGICAL SAMPLE Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2016-05-25 EP claimed
EP-2839873-A1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF Wang, Zhijun (CN) 2015-02-25 EP claimed
WO-2015007317-A1 MEANS AND METHODS FOR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) ANALYSIS IN A BIOLOGICAL SAMPLE Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2015-01-22 WO claimed
EP-1700631-B1 Improved process for treating gases containing hydrogen sulfur and sulfur dioxide INST FRANCAIS DU PETROLE (FR) 2010-06-30 EP claimed
EP-1700631-A1 Improved process for treating gases containing hydrogen sulfur and sulfur dioxide Institut Français du Pétrole (FR) 2006-09-13 EP claimed
CN-1083805-A 7-(replacement)-9-[(substituted glycyl) amido]-6-demethylation-6-deoxytetra cycline AMERICAN CYANAMID CO (US) 1994-03-16 CN claimed
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 EP claimed
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 CN disclosed
CN-117980273-A Solid phosphorus-free scale and corrosion inhibitor composition for cooling water treatment 埃科莱布美国股份有限公司 2024-05-03 CN disclosed
CN-117897392-A Aqueous solid phase peptide synthesis 多肽实验室(PPL)控股公司 2024-04-16 CN disclosed
CN-117886814-A PD-1/PD-L1 small molecule inhibitor and application thereof in medicines 广东东阳光药业股份有限公司 2024-04-16 CN disclosed
CN-117715914-A Camptothecin analogs, conjugates, and methods of use 酵活英属哥伦比亚有限公司 2024-03-15 CN disclosed
CN-1092411-A The method of the formylimidazoles that preparation replaces SMITHKLINE BEECHAM CORP (US) 1994-09-21 CN disclosed
CN-1083805-A 7-(replacement)-9-[(substituted glycyl) amido]-6-demethylation-6-deoxytetra cycline AMERICAN CYANAMID CO (US) 1994-03-16 CN disclosed
CN-1083473-A New imidazolium compounds and pharmaceutical composition thereof SMITHKLINE BEECHAM CORP (US) 1994-03-09 CN disclosed
EP-0526486-A1 NON-LINEAR OPTICAL DEVICE. SECR DEFENCE BRIT (GB) 1993-02-10 EP disclosed
WO-1991016657-A1 NON-LINEAR OPTICAL DEVICE THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1991-10-31 WO disclosed
CN-1039440-A The preparation method of tissue plasminogen activator's analogue NOVO NORDISK AS (DK) 1990-02-07 CN disclosed