SCHEMBL31552871

SCHEMBL31552871

CO[C@@]1(O)[C@H](OP(=O)(O)O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 8/20 0.51
P2RY4 P51582 6/20 0.51
SLC28A1 O00337 1/20 0.47
SLC28A2 O43868 1/20 0.47
SLC29A1 Q99808 1/20 0.47
SLC28A3 Q9HAS3 1/20 0.47
P2RY14 Q15391 8/20 0.46
P2RY6 Q15077 6/20 0.46
POLA1 P09884 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31544059 0.91 SLC28A1 (0.47) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL31598954 0.88 P2RY2 (0.60) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL31750991 0.86 P2RY2 (0.49) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL15329048 0.85 POLA1 (0.52) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL31657660 0.84 P2RY2 (0.52) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL93614 0.84 SLC28A1 (0.54) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL29414441 0.82 SLC28A1 (0.46) P2RY2P2RY4SLC28A1SLC28A2SLC29A1
SCHEMBL38661234 0.80 P2RY2 (0.64) P2RY2P2RY4P2RY14P2RY6POLA1
SCHEMBL31552872 0.80 PDE3A (0.54) P2RY2SLC29A1POLA1
SCHEMBL564840 0.79 P2RY2 (0.45) P2RY2P2RY4SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF HANGZHOU TIANLONG PHARMACEUTICAL CO., LTD. (CN) 2026-05-07 US disclosed
EP-4678747-A2 DOUBLE-STRANDED RNAI AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF Hangzhou Tianlong Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
WO-2025077949-A1 MODIFICATION TEMPLATE FOR IMPROVING INHIBITORY EFFECT OF DOUBLE-STRANDED OLIGONUCLEOTIDE ON TARGET GENE, COMBINATION THEREOF AND USE THEREOF 杭州天龙药业有限公司 2025-04-17 WO disclosed
WO-2025061911-A1 METHODS OF PRODUCING NUCLEOTIDE TRIPHOSPHATES (NTPS) GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF NSUN2, EIF2AK2, METTL16 P2RY2 4189/4885P2RY4 4275/4885SLC28A1 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.