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METTL16

RNA N(6)-adenosine-methyltransferase METTL16 · Q86W50 · METTL16 on Sugi Atlas →

24 patent compounds predicted against METTL16, 18 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL11096401 SCHEMBL11096401 0.38 2/20
SCHEMBL15102161 SCHEMBL15102161 0.48 1/20
SCHEMBL18699211 SCHEMBL18699211 0.46 1/20
SCHEMBL3594484 SCHEMBL3594484 0.45 1/20
SCHEMBL30232255 SCHEMBL30232255 0.45 1/20
SCHEMBL6315053 SCHEMBL6315053 0.45 1/20
SCHEMBL6315054 SCHEMBL6315054 0.45 1/20
SCHEMBL14235677 SCHEMBL14235677 0.44 1/20
SCHEMBL4551869 SCHEMBL4551869 0.44 1/20
SCHEMBL4551870 SCHEMBL4551870 0.44 1/20
SCHEMBL4551871 SCHEMBL4551871 0.44 1/20
SCHEMBL7094984 SCHEMBL7094984 0.42 1/20
SCHEMBL14214143 SCHEMBL14214143 0.42 1/20
SCHEMBL23055390 SCHEMBL23055390 0.42 1/20
SCHEMBL7482341 SCHEMBL7482341 0.41 1/20
SCHEMBL23055608 SCHEMBL23055608 0.41 1/20
SCHEMBL6327328 SCHEMBL6327328 0.40 1/20
SCHEMBL6327330 SCHEMBL6327330 0.40 1/20

Clinical trials — most relevant to METTL16 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Prognosis of METTL-14 in Endometrial Carcinoma nanNOT_YET_RECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Molecular Profiling for Risk Stratification in Appendiceal Cancer nanRECRUITING
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Search for Bovine miRNA Transference to Humans nanCOMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
Apelin12 in Acne Vulgaris nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 nanCOMPLETED
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Timisnar - Biomarkers Substudy (Timisnar-mirna) nanUNKNOWN
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis nanRECRUITING
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas nanACTIVE_NOT_RECRUITING
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Research on the Early and Prognosis Diagnosis of Vascular Dementia nanRECRUITING
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT nanUNKNOWN
LIPCAR, Cuproptosis, and Α-SMA in the Pathogenesis of AMI and Remodeling nanNOT_YET_RECRUITING
MicroRNAs as Biomarkers for Obstructive Sleep Apnea nanRECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Maternal Hypertriglyceridaemia Study nanUNKNOWN
Circulating Non-coding RNAs and Cardiovascular Outcomes in Patients With Dyslipidemia and Atherosclerosis nanUNKNOWN
Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP) nanUNKNOWN
Circulating lncRNA and CV Morbidities in CKD and ESRD nanUNKNOWN
Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery nanRECRUITING
Bace1as Role in Heart Failure (BACE1AS-HF) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a METTL16 binder may also engage these)

ProteinNameSimilarity
Q9CQG2 — 1.000 Q9CQG2 →
Q5ZIA0 — 0.998 Q5ZIA0 →
Q6DC64 — 0.988 Q6DC64 →
Q6GR37 — 0.973 Q6GR37 →
Q9UPR3 — 0.962 Q9UPR3 →
Q7Z624 — 0.962 Q7Z624 →
Q4R8W3 — 0.961 Q4R8W3 →
Q2PFX0 — 0.960 Q2PFX0 →
Q6ZPY2 — 0.960 Q6ZPY2 →
Q8NHH1 — 0.959 Q8NHH1 →
P21580 — 0.958 P21580 →
Q5ZLS7 — 0.957 Q5ZLS7 →
PTAR1 Protein prenyltransferase alpha subunit repeat-containing protein 1 0.957 landscape →
O94888 — 0.957 O94888 →
Q5REY7 — 0.956 Q5REY7 →
Q8CIW5 — 0.956 Q8CIW5 →
Q6DFV5 — 0.955 Q6DFV5 →
Q9BYE7 — 0.955 Q9BYE7 →
Q96RR1 — 0.954 Q96RR1 →
Q5XI70 — 0.954 Q5XI70 →
Q8TBP0 — 0.954 Q8TBP0 →
Q99NA9 — 0.954 Q99NA9 →
O54804 — 0.954 O54804 →
Q8NFG4 — 0.954 Q8NFG4 →
Q3V038 — 0.953 Q3V038 →
A4Q9F4 — 0.953 A4Q9F4 →
Q01134 — 0.953 Q01134 →
HIRA Protein HIRA 0.953 landscape →
O95260 — 0.953 O95260 →
Q9P260 — 0.952 Q9P260 →