Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554372 | 0.91 | USP30 (0.43) | USP30CHEK1CNR1CNR2KDM4E | |
| SCHEMBL31554319 | 0.91 | CHEK1 (0.44) | USP30CHEK1CNR1CNR2KDM4E | |
| SCHEMBL31554347 | 0.89 | CHEK1 (0.49) | USP30CHEK1 | |
| SCHEMBL31554330 | 0.88 | CHEK1 (0.43) | USP30CHEK1KDM4EMEN1MAPT | |
| SCHEMBL31554336 | 0.88 | RAB9A (0.51) | USP30CHEK1CNR1CNR2MEN1 | |
| SCHEMBL31554339 | 0.88 | BTK (0.40) | USP30CHEK1CNR1CNR2JAK1 | |
| SCHEMBL31554334 | 0.87 | CNR1 (0.42) | USP30CNR1CNR2KDM4EMAPT | |
| SCHEMBL31532654 | 0.86 | USP30 (0.59) | USP30CNR1CNR2 | |
| SCHEMBL31532575 | 0.86 | USP30 (0.59) | USP30CNR1CNR2 | |
| SCHEMBL31554391 | 0.85 | CHEK1 (0.41) | USP30CHEK1CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099238-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-15 | — | — | WO | disclosed |