Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 11/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 6/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968020 | 0.85 | AXL (0.48) | AXLMETMAP4K4 | |
| SCHEMBL3484744 | 0.84 | EPHB3 (0.39) | IRAK4MEN1KMT2AEPHB3JAK2 | |
| SCHEMBL16863199 | 0.82 | AXL (0.54) | AXLMET | |
| SCHEMBL31554493 | 0.79 | HSPB1 (0.50) | IRAK4AXLMEN1KMT2AEPHB3 | |
| SCHEMBL4818237 | 0.76 | MAP4K4 (0.48) | AXLMETMAP4K4 | |
| SCHEMBL16863308 | 0.75 | AXL (0.52) | AXLMEN1KMT2AJAK2MET | |
| SCHEMBL16863355 | 0.74 | AXL (0.44) | AXLMET | |
| SCHEMBL30059265 | 0.73 | MEN1 (0.40) | AXLMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25968454 | 0.73 | MEN1 (0.40) | AXLMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15821714 | 0.72 | MEN1 (0.54) | MEN1KMT2ARHEBKDM4EMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096463-A1 | PLK4 MODULATORS | VIBLIOME THERAPEUTICS, LLC (US) | 2025-05-08 | — | — | WO | disclosed |