SCHEMBL31554657

SCHEMBL31554657

Cn1nc(C2CCC(=O)NC2=O)c2ccc(NC3CCN(C(=O)CNC(=O)OC(C)(C)C)CC3)cc21

nearest known ligand 0.80

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 15/20 0.80
▸ CRBN Q96SW2 15/20 0.80
▸ SIGMAR1 Q99720 1/20 0.38
▸ FNTA P49354 1/20 0.38
▸ FNTB P49356 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29984027 0.89 DDB1 (1.00) DDB1CRBNALDH1A1
SCHEMBL20805490 0.89 DDB1 (1.00) DDB1CRBNALDH1A1
SCHEMBL30705885 0.88 DDB1 (0.73) DDB1CRBN
SCHEMBL30029207 0.87 DDB1 (0.81) DDB1CRBN
SCHEMBL31520793 0.87 DDB1 (0.78) DDB1CRBNMAPK8
SCHEMBL25169692 0.85 DDB1 (0.79) DDB1CRBN
Hydrochloric Acid SCHEMBL31554681 0.85 DDB1 (0.73) DDB1CRBN
SCHEMBL19585779 0.84 DDB1 (0.79) DDB1CRBN
SCHEMBL30661576 0.83 DDB1 (0.72) DDB1CRBN
SCHEMBL30705944 0.82 DDB1 (0.83) DDB1CRBNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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