Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574484 | 0.93 | OPRM1 (0.51) | HRH3CYP3A4CYP2C19OPRM1OPRD1 | |
| SCHEMBL21874277 | 0.87 | CYP3A4 (0.45) | CYP3A4CYP2C19OPRM1OPRD1OPRK1 | |
| SCHEMBL10319703 | 0.84 | OPRM1 (0.55) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12317609 | 0.84 | OPRM1 (0.55) | HRH3CYP3A4CYP2C19OPRM1OPRD1 | |
| SCHEMBL29262933 | 0.83 | OPRM1 (0.46) | HRH3CYP3A4CYP2C19OPRM1OPRD1 | |
| SCHEMBL2778410 | 0.83 | SLC6A4 (0.54) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21874209 | 0.83 | SLC6A4 (0.54) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL29151340 | 0.83 | SLC6A4 (0.54) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL28970507 | 0.83 | SLC6A4 (0.54) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL29151325 | 0.83 | SLC6A4 (0.54) | HRH3OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068943-A1 | KAT6 INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-03 | — | — | WO | disclosed |