Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729440 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL27092799 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL2724346 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL2724344 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL4550798 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL31015264 | 0.77 | SMPD3 (0.39) | KMT2AALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL2722843 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL2722842 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL10183489 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL31263645 | 0.74 | KDM4E (0.46) | KMT2AALDH1A1KDM4EGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068354-A1 | SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-03 | — | — | WO | disclosed |