Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 11/20 | 0.80 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373368 | 1.00 | WEE1 (0.80) | WEE1TNK2EGFRKCNH2JAK2 | |
| SCHEMBL29859559 | 0.95 | WEE1 (0.79) | WEE1TNK2EGFRKCNH2JAK2 | |
| SCHEMBL21373421 | 0.95 | WEE1 (0.79) | WEE1TNK2EGFRKCNH2JAK2 | |
| SCHEMBL21373428 | 0.95 | WEE1 (0.76) | WEE1TNK2EGFR | |
| SCHEMBL31556915 | 0.95 | WEE1 (0.76) | WEE1TNK2EGFR | |
| SCHEMBL21373422 | 0.92 | WEE1 (0.72) | WEE1TNK2EGFR | |
| SCHEMBL31557265 | 0.92 | WEE1 (0.72) | WEE1TNK2EGFR | |
| SCHEMBL29506507 | 0.90 | WEE1 (0.65) | WEE1TNK2EGFRKCNH2JAK2 | |
| SCHEMBL21373312 | 0.90 | WEE1 (0.65) | WEE1TNK2EGFRKCNH2JAK2 | |
| SCHEMBL21373401 | 0.90 | WEE1 (0.69) | WEE1TNK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074275-A1 | COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS AND WEE1 INHIBITORS | REPARE THERAPEUTICS, INC. (CA) | 2025-04-10 | — | — | WO | disclosed |