⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569417 | 0.72 | — | — | |
| SCHEMBL13013453 | 0.72 | — | — | |
| SCHEMBL15672003 | 0.72 | — | — | |
| SCHEMBL5472363 | 0.72 | — | — | |
| SCHEMBL3618753 | 0.72 | — | — | |
| SCHEMBL17165129 | 0.72 | — | — | |
| SCHEMBL5475474 | 0.69 | CYP1A2 (0.31) | — | |
| SCHEMBL12990681 | 0.69 | — | — | |
| SCHEMBL23131897 | 0.67 | — | — | |
| SCHEMBL12580604 | 0.67 | SIGMAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798230-A | Indolone compounds and application thereof in treating acute and chronic liver diseases and promoting tissue repair | 中国药科大学 | 2025-04-11 | — | — | CN | claimed |
| CN-119798230-A | Indolone compounds and application thereof in treating acute and chronic liver diseases and promoting tissue repair | 中国药科大学 | 2025-04-11 | — | — | CN | disclosed |