Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31559321 | 0.94 | HDAC1 (0.42) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL31559556 | 0.83 | SMN1; SMN2 (0.50) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL30702529 | 0.82 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL30702528 | 0.82 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL31559401 | 0.82 | SMN1; SMN2 (0.50) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL29087318 | 0.80 | HDAC1 (0.44) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL31559845 | 0.79 | SMN1; SMN2 (0.46) | HDAC1HDAC6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31559392 | 0.78 | SMN1; SMN2 (0.46) | HDAC1HDAC6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31559505 | 0.77 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL2876427 | 0.77 | CTSD (0.51) | HDAC1HDAC6HDAC3HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090514-A1 | COVALENT SARM1 INHIBITORS | NURA BIO, INC. (US) | 2025-05-01 | — | — | WO | disclosed |