Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560534 | 0.87 | HDAC4 (0.41) | HDAC4KDM4EALDH1A1MAPTSLC6A1 | |
| SCHEMBL31560467 | 0.86 | HDAC4 (0.40) | HDAC4ALDH1A1MAPTLMNA | |
| SCHEMBL31560680 | 0.85 | HDAC4 (0.38) | HDAC4GAAKDM4ELMNAPOLB | |
| SCHEMBL31560599 | 0.85 | HDAC4 (0.38) | HDAC4GAAKDM4EALDH1A1HTT | |
| SCHEMBL31560665 | 0.85 | HDAC4 (0.38) | HDAC4GAAKDM4ESLC6A1LMNA | |
| SCHEMBL31560493 | 0.83 | HDAC4 (0.43) | HDAC4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL31560697 | 0.81 | HDAC4 (0.43) | HDAC4ALDH1A1NPSR1 | |
| SCHEMBL31560757 | 0.80 | ALDH1A1 (0.40) | HDAC4KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL31560540 | 0.79 | HDAC4 (0.39) | HDAC4ALDH1A1MAPTLMNA | |
| SCHEMBL31560561 | 0.78 | HDAC4 (0.41) | HDAC4ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | claimed |
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |