SCHEMBL31562487

SCHEMBL31562487

CCOC(=O)Cc1ccc(C2OCCO2)c(OCc2ccc(OC)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MAOB P27338 2/20 0.41
▸ ALDH1A1 P00352 5/20 0.39
▸ MAPT P10636 2/20 0.39
▸ GAA P10253 1/20 0.39
▸ LIPE Q05469 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ LMNA P02545 2/20 0.39
▸ HTT P42858 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ KLK7 P49862 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574783 0.90 SMPD1 (0.42) ALDH1A1MAPTGAALMNAHTT
SCHEMBL25385517 0.90 SMPD1 (0.42) ALDH1A1MAPTGAALMNAHTT
SCHEMBL30574832 0.87 PTGS1 (0.48) ALDH1A1GAAKDM4ETSHRLMNA
SCHEMBL25385232 0.87 PTGS1 (0.48) ALDH1A1GAAKDM4ETSHRLMNA
SCHEMBL25385411 0.86 MAOB (0.47) MEN1KMT2AMAOBALDH1A1MAPT
SCHEMBL30574954 0.86 MAOB (0.47) MEN1KMT2AMAOBALDH1A1MAPT
SCHEMBL25385151 0.83 FFAR1 (0.41) MAOBMAPTHPGDSMN1; SMN2
SCHEMBL30574831 0.83 FFAR1 (0.41) MAOBMAPTHPGDSMN1; SMN2
SCHEMBL25385433 0.82 MAOB (0.37) MAOBALDH1A1MAPTTSHRLMNA
SCHEMBL30574828 0.82 MAOB (0.37) MAOBALDH1A1MAPTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 — — US disclosed
WO-2025090658-A2 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-05-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF CDK2, CDK20, CDK1 MEN1 2982/4885KMT2A 85/4885MAOB 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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