Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385433 | 1.00 | MAOB (0.37) | MAOBALDH1A1SMN1; SMN2HDAC8SLC2A1 | |
| SCHEMBL30574953 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2HDAC8SLC2A1HPGD | |
| SCHEMBL25385144 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2HDAC8SLC2A1HPGD | |
| SCHEMBL30574764 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HDAC8HPGDPPARD | |
| SCHEMBL25385011 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HDAC8HPGDPPARD | |
| SCHEMBL31562487 | 0.82 | MEN1 (0.43) | MAOBALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL25384316 | 0.81 | PPARG (0.40) | ALDH1A1SMN1; SMN2HPGDPPARDLMNA | |
| SCHEMBL30574845 | 0.81 | PPARG (0.40) | ALDH1A1SMN1; SMN2HPGDPPARDLMNA | |
| SCHEMBL30313200 | 0.81 | ALDH1A1 (0.44) | MAOBALDH1A1HDAC8PPARDLMNA | |
| SCHEMBL25385151 | 0.80 | FFAR1 (0.41) | MAOBSMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | Terremoto Biosciences, Inc (US) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023168291-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |