Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199092 | 0.92 | MAOB (0.50) | HDAC8SMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL21957648 | 0.91 | HDAC8 (0.54) | HDAC8SMN1; SMN2MAPTL3MBTL1NPC1 | |
| SCHEMBL30230244 | 0.89 | SMN1; SMN2 (0.44) | HDAC8SMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL26047483 | 0.86 | HDAC8 (0.50) | HDAC8SMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL15348526 | 0.86 | ERN1 (0.63) | HDAC8SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL12581731 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL29846122 | 0.83 | HDAC8 (0.53) | HDAC8SMN1; SMN2LMNAPTPN1 | |
| SCHEMBL28491464 | 0.83 | HDAC8 (0.53) | HDAC8SMN1; SMN2LMNAPTPN1 | |
| SCHEMBL13744497 | 0.82 | SMN1; SMN2 (0.51) | HDAC8SMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL23835465 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289789-A1 | REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. | 2025-09-18 | — | — | US | disclosed |
| WO-2025090658-A2 | REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289789-A1 | REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF | CDK2, CDK20, CDK1 | HDAC8 117/4885SMN1; SMN2 2895/4885MAPT 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.