Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31564694 | 1.00 | RORC (0.38) | RORCBUB1KMT2ASLC22A12MEN1 | |
| SCHEMBL31564685 | 0.84 | KMT2A (0.45) | RORCBUB1KMT2ASLC22A12MEN1 | |
| SCHEMBL31564564 | 0.82 | SLC22A12 (0.39) | RORCBUB1KMT2ASLC22A12MEN1 | |
| SCHEMBL16611151 | 0.81 | CNR1 (0.40) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL25757051 | 0.76 | RXFP1 (0.33) | — | |
| SCHEMBL30498069 | 0.73 | ADORA2A (0.35) | ALDH1A1LMNA | |
| SCHEMBL25756716 | 0.73 | ADORA2A (0.35) | ALDH1A1LMNA | |
| SCHEMBL9370888 | 0.73 | GRM2 (0.45) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL31272944 | 0.73 | CNR1 (0.45) | BUB1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL883677 | 0.73 | CNR1 (0.45) | BUB1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096453-A1 | COMPOUNDS FOR THE TREATMENT OF KIDNEY DISEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-05-08 | — | — | WO | disclosed |