Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835083 | 1.00 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL1527302 | 0.79 | NOTUM (0.52) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL3397331 | 0.79 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL14272674 | 0.78 | NOTUM (0.51) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL1151123 | 0.78 | NOTUM (0.70) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL10477477 | 0.78 | NOTUM (0.70) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL29453277 | 0.76 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL931955 | 0.76 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL21808239 | 0.76 | KRAS (0.50) | — | |
| SCHEMBL20905232 | 0.76 | TFPI2 (0.47) | NOTUMTFPI2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164495-B | Covalent targeting of E3 ligases | 加利福尼亚大学董事会 | 2025-04-22 | — | — | CN | disclosed |