Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31565005 | 1.00 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL1527302 | 0.79 | NOTUM (0.52) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL3397331 | 0.79 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL14272674 | 0.78 | NOTUM (0.51) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL1151123 | 0.78 | NOTUM (0.70) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL10477477 | 0.78 | NOTUM (0.70) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL29453277 | 0.76 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL931955 | 0.76 | TSHR (0.69) | NOTUMTSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL21808239 | 0.76 | KRAS (0.50) | — | |
| SCHEMBL20905232 | 0.76 | TFPI2 (0.47) | NOTUMTFPI2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1709921-A | Resin of zinc acrylate or copper acrylate containing indole function group, its preparation and use | CHINESE OCEANOGRAPHY UNIV (CN) | 2005-12-21 | — | — | CN | claimed |
| US-20250120982-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-04-17 | — | — | US | disclosed |
| US-12161648-B2 | Covalent targeting of E3 ligases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-10 | — | — | US | disclosed |
| WO-2024097262-A1 | CHEMOPROTEOMIC CAPTURE OF RNA BINDING ACTIVITY IN LIVING CELLS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20240103005-A1 | N-ACRYLOYLINDOLES AND METHODS OF USE | VERSITECH LIMITED (CN) | 2024-03-28 | — | — | US | disclosed |
| US-20240103005-A1 | N-ACRYLOYLINDOLES AND METHODS OF USE | VERSITECH LIMITED (CN) | 2024-03-28 | — | — | US | disclosed |
| CN-117126096-A | N-acryloylindoles and methods of use | 香港大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-117126096-A | N-acryloylindoles and methods of use | 香港大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-117126096-A | N-acryloylindoles and methods of use | 香港大学 | 2023-11-28 | — | — | CN | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
| WO-2019183600-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019075386-A1 | MTORC1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-18 | — | — | WO | disclosed |
| US-20190112268-A1 | mTORC1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-18 | — | — | US | disclosed |
| CN-1709921-B | Resin of zinc acrylate or copper acrylate containing indole function group, its preparation and use | OCEAN UNIV CHINA | 2011-09-28 | — | — | CN | disclosed |
| CN-1709921-A | Resin of zinc acrylate or copper acrylate containing indole function group, its preparation and use | CHINESE OCEANOGRAPHY UNIV (CN) | 2005-12-21 | — | — | CN | disclosed |
| EP-0091039-B1 | ANTI-FOULING AGENT | Nitto Kasei Co., Ltd. (JP) | 1986-10-01 | — | — | EP | disclosed |
| US-4598156-A | Process for producing indoles unsubstituted in the 2,3-position and N(3-chloropropionyl)indole produced thereby | CIBA GEIGY CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |
| US-4526932-A | Copolymer containing N-coordinated triorganotin compound | NITTO KASEI CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0091039-A2 | Anti-fouling agent | Nitto Kasei Co., Ltd. (JP) | 1983-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240103005-A1 | N-ACRYLOYLINDOLES AND METHODS OF USE | NAT1, DDIT3, ACR | NOTUM 3260/4885TSHR 3784/4885RAB9A 3380/4885 |
| US-12161648-B2 | Covalent targeting of E3 ligases | RNF114, RNF4, RNF168 | NOTUM 2977/4885TSHR 4065/4885RAB9A 2224/4885 |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | NOTUM 4238/4885TSHR 4601/4885RAB9A 223/4885 |
| US-20190112268-A1 | mTORC1 MODULATORS | MTOR, RPTOR, RICTOR | NOTUM 3808/4885TSHR 3686/4885RAB9A 439/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | NOTUM 4238/4885TSHR 4601/4885RAB9A 223/4885 |
| US-20250120982-A1 | COVALENT TARGETING OF E3 LIGASES | STUB1, XIAP, RBX1 | NOTUM 3544/4885TSHR 4386/4885RAB9A 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.