Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | POLB | P06746 | 4/20 | 0.80 |
| ▸ | KLK7 | P49862 | 1/20 | 0.80 |
| ▸ | GFER | P55789 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960111 | 1.00 | MEN1 (0.80) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1960113 | 1.00 | MEN1 (0.80) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL2119658 | 0.92 | MEN1 (0.95) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1965484 | 0.92 | MEN1 (0.95) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1963762 | 0.92 | MEN1 (0.72) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1963763 | 0.92 | MEN1 (0.72) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1965482 | 0.92 | MEN1 (0.95) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1961703 | 0.90 | MEN1 (0.74) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1961700 | 0.90 | MEN1 (0.74) | MEN1KMT2APOLBKLK7GFER | |
| SCHEMBL1962693 | 0.90 | TP53 (0.76) | MEN1KMT2APOLBKLK7GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3844152-B1 | SUBSTITUTED HETEROCYCLES AS C-MYC TARGETING AGENTS | UNIV NORTHWESTERN (US) | 2025-05-07 | — | — | EP | disclosed |