Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966871 | 1.00 | NR1H2 (0.60) | NR1H2USP2SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL14325258 | 1.00 | NR1H2 (0.60) | NR1H2USP2SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL15495236 | 1.00 | NR1H2 (0.60) | NR1H2USP2SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL16348045 | 0.93 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2HPGDHDAC1 | |
| SCHEMBL17518861 | 0.88 | GPR119 (0.49) | NR1H2HPGDHDAC1HDAC2GPR119 | |
| SCHEMBL15078689 | 0.88 | GPR119 (0.49) | NR1H2HPGDHDAC1HDAC2GPR119 | |
| SCHEMBL22873431 | 0.87 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2HPGDGPR119 | |
| SCHEMBL25269687 | 0.86 | NR1H2 (0.54) | NR1H2USP2SMN1; SMN2HPGDGPR119 | |
| SCHEMBL23763034 | 0.86 | GPR119 (0.57) | USP2SMN1; SMN2HPGDGPR119RECQL | |
| SCHEMBL17518845 | 0.85 | MEN1 (0.51) | NR1H2USP2SMN1; SMN2HPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |