SCHEMBL31569014

SCHEMBL31569014

CC(C)(C)OC(=O)NCCc1ncccc1C(=O)C(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NQO2 P16083 1/20 0.40
CYP3A4 P08684 1/20 0.40
AKT1 P31749 1/20 0.39
MALT1 Q9UDY8 1/20 0.39
IDO1 P14902 2/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
BCHE P06276 1/20 0.38
KCNA5 P22460 1/20 0.38
NAMPT P43490 1/20 0.38
LMNA P02545 2/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GFER P55789 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569082 0.85 KDM4E (0.43) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL34469093 0.85 AKT1 (0.42) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL31569428 0.84 ATR (0.45) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL31569411 0.83 KDM4E (0.42) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL3081832 0.82 KDM4E (0.44) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL31569005 0.81 KDM4E (0.40) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL25056476 0.80 KDM4E (0.45) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL5592422 0.80 NQO2 (0.47) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL31569010 0.80 CKS1B (0.40) KDM4EL3MBTL1NQO2CYP3A4AKT1
SCHEMBL13095179 0.78 KDM4E (0.43) KDM4EL3MBTL1NQO2CYP3A4AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D KDM4E 3666/4885L3MBTL1 1777/4885NQO2 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.