SCHEMBL31569029

SCHEMBL31569029

C[C@@H]1Cc2ncsc2CN1C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.36
▸ PTPN1 P18031 1/20 0.35
▸ MAP4K4 O95819 1/20 0.35
▸ GPR119 Q8TDV5 6/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ UCHL1 P09936 1/20 0.32
▸ SCN4A P35499 1/20 0.32
▸ HDAC1 Q13547 1/20 0.32
▸ NAMPT P43490 1/20 0.32
▸ NR1H2 P55055 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30740130 0.78 MAPK1 (0.45) MAPK1GPR119NR1H2
SCHEMBL31568970 0.77 SCN4A (0.35) PTPN1MAP4K4MEN1KMT2ASCN4A
SCHEMBL31569367 0.76 SCN4A (0.36) PTPN1MAP4K4MEN1KMT2AUCHL1
SCHEMBL31569400 0.76 SCN4A (0.36) PTPN1MAP4K4MEN1KMT2ASCN4A
SCHEMBL24061284 0.75 SCN4A (0.49) MAP4K4GPR119MEN1KMT2ASCN4A
SCHEMBL31568968 0.75 SCN4A (0.36) MAP4K4MEN1KMT2ASCN4A
SCHEMBL22647477 0.75 SCN4A (0.49) MAP4K4GPR119MEN1KMT2ASCN4A
SCHEMBL30916184 0.75 MAPK1 (0.58) MAPK1NR1H2
SCHEMBL741598 0.75 MAPK1 (0.58) MAPK1NR1H2
SCHEMBL31569524 0.74 MEN1 (0.37) MAP4K4GPR119MEN1KMT2ASCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 — — US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D MAPK1 1283/4885PTPN1 2093/4885MAP4K4 2227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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