Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569805 | 0.85 | DDB1 (0.56) | DDB1CRBNPDE3BPDE3A | |
| SCHEMBL31569849 | 0.83 | DDB1 (0.59) | DDB1CRBNOPRM1OPRD1OGFRL1 | |
| SCHEMBL31569757 | 0.82 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL31569727 | 0.81 | DDB1 (0.59) | DDB1CRBNNAMPTOPRM1OPRD1 | |
| SCHEMBL26641335 | 0.81 | DDB1 (0.66) | DDB1CRBNBACE1 | |
| SCHEMBL27225148 | 0.81 | DDB1 (0.66) | DDB1CRBNBACE1 | |
| SCHEMBL31444146 | 0.81 | DDB1 (0.66) | DDB1CRBNBACE1 | |
| SCHEMBL23301226 | 0.80 | DDB1 (0.67) | DDB1CRBNNAMPT | |
| SCHEMBL21876964 | 0.80 | DDB1 (0.67) | DDB1CRBNNAMPT | |
| SCHEMBL31569846 | 0.80 | HTR3A (0.47) | DDB1CRBNNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |