Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569595 | 0.93 | DDB1 (0.55) | DDB1CRBNGPR119 | |
| SCHEMBL31569884 | 0.86 | DDB1 (0.58) | DDB1CRBNGPR119 | |
| SCHEMBL31569618 | 0.82 | DDB1 (0.55) | DDB1CRBNGPR119 | |
| SCHEMBL31570018 | 0.81 | SOS1 (0.55) | DDB1CRBNTP53 | |
| SCHEMBL31569805 | 0.81 | DDB1 (0.56) | DDB1CRBNGPR119 | |
| SCHEMBL30830951 | 0.81 | CRBN (0.61) | DDB1CRBNGPR119TP53 | |
| SCHEMBL31569660 | 0.80 | DDB1 (0.55) | DDB1CRBN | |
| SCHEMBL30831070 | 0.79 | DDB1 (0.60) | DDB1CRBN | |
| SCHEMBL31569757 | 0.79 | DDB1 (0.58) | DDB1CRBNGPR119 | |
| SCHEMBL31569995 | 0.78 | TP53 (0.51) | GPR119TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |