Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569757 | 0.93 | DDB1 (0.58) | DDB1CRBNGPR119CNR2 | |
| SCHEMBL31569931 | 0.86 | DDB1 (0.55) | DDB1CRBNGPR119 | |
| SCHEMBL31569727 | 0.82 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31569849 | 0.81 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31570006 | 0.80 | GPR119 (0.50) | DDB1CRBNGPR119 | |
| SCHEMBL31569731 | 0.80 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL26641335 | 0.80 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL27225148 | 0.80 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL31444146 | 0.80 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL25337718 | 0.80 | GPR119 (0.47) | DDB1CRBNGPR119MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |